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17621170138
17621170138
詳細介紹
| 品牌 | Leinco Technologies | 貨號 | T353 |
|---|---|---|---|
| 規格 | 100mg | 供貨周期 | 一個月 |
| 應用領域 | 醫療衛生,化工,生物產業,制藥/生物制藥 |
Leinco Technologies：TCR V gamma 2 抗體
V gamma 2 TCR Monoclonal Antibody (UC3-10A6), Functional Grade, In Vivo GOLD™
Vγ2 TCR單克隆抗體（UC3-10A6），功能級，體內GOLD™
特異性：該抗體與攜帶Vgamma 2 T細胞受體（TCR）的T淋巴細胞反應。
內毒素水平：通過LAL法測定，<1.0 EU/mg。
純度：通過SEC分析，單體含量≥95%，通過SDS Page分析，單體含量>95%。
Specificity: This antibody reacts with Vgamma 2 T-Cell Receptor (TCR)-bearing T lymphocytes.
Endotoxin Level: <1.0 EU/mg as determined by the LAL method.
Purity: ≥95% monomer by analytical SEC and >95% by SDS Page.
Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage: This antibody is stable for at least one week when stored sterile at 2-8C. For long term storage aseptically aliquot in working volumes without diluting and store at -20C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
該抗體在2-8C無菌儲存時至少穩定一周。用于長期無菌儲存，按工作體積等分，無需稀釋，并在-20℃的手動除霜冰箱中儲存。避免反復凍融循環。
The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease. Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). A small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than alpha-beta T cells. Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.僅用于科研。不用于診斷過程。未經明確授權不得轉售。
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